COA Process

The BioLongevity Labs COA Process

Every compound BioLongevity Labs ships carries a lot-matched certificate of analysis issued by an independent testing laboratory.

The certificates themselves are published in full in the COA Library, open to anyone, with no account and no purchase required.

This page explains how that testing works, what each certificate reports, how to read the numbers on your own document, and how to verify it directly with the laboratory that wrote it.

How the Lookup Works

How to Find Your Certificate

Four steps, and the whole process takes under a minute.

Locate your lot number

The lot number is printed on the vial label and repeated on the outer carton. It is the same identifier that appears on the certificate.

Open the COA Library

Use the product dropdown to filter the library. Products are listed by the name shown on the label, including blends and multi-vial sets.

Match the lot number

Each certificate is titled with the compound name followed by its lot number in parentheses. Match the number on your vial to the number in the title.

Open the document

Click the certificate to view it full size. From there you can save, print, or forward it.

If your lot number does not appear, contact help@biolongevitylabs.com with a photo of the label and the certificate will be sent directly.

Browse the COA Database

The full certificate library lives on its own page. It holds the current record for every lot in distribution, plus the endotoxin reports issued as standalone documents.

Open the COA Library

Certificates are ordered newest first and filter by product. Older lots stay published rather than being replaced, so the full testing history for each compound remains available.

What the Certificate Reports

What a Peptide Certificate of Analysis Confirms

A peptide certificate of analysis is the analytical record for one production lot. It reports what the material is, how pure it is, how much of it is in the vial, and what it should look like.

Five categories appear across the documents in the library.

Report

Analytical method

What it confirms

Identity

Mass spectrometry

The measured molecular weight matches the target sequence

Purity

Liquid chromatography with mass spectrometry (LC-MS or UHPLC-MS)

The percentage of target compound relative to related substances

Quantity

Liquid chromatography against a calibration curve

The amount of compound in the vial compared to the labeled quantity

Appearance

Visual inspection

The physical form and color of the material match the compound

Endotoxin

Limulus amebocyte lysate assay

Bacterial endotoxin content in the finished lot, against a threshold of 0.05 EU/mL or lower

Identity, purity, and quantity describe the synthesis itself. Endotoxin describes the handling, filling, and storage steps that follow it.

Both are important when material is going into a controlled protocol, which is why endotoxin results are always published, whether they sit on the certificate itself or in a separate report.

Why the Certificates Look Different

BioLongevity Labs uses more than one independent laboratory, and each one issues its documents in its own house format. The layout, the section names, and the field labels differ between them.

The reported measurements do not. Identity, purity, quantity, & appearance appear on every certificate regardless of which laboratory produced it.

Who Issues the COAs?

Testing Is Done Outside the Company

BioLongevity Labs does not test its own material. Samples are sent to independent analytical laboratories, including MDx BioAnalytical Laboratory, Inc. and BioRegen, and the certificates published in the library are the documents those laboratories return.

Three points explain why that separation is worth the added step.

An Outside Lab Has No Stake in the Result

A supplier grading its own output has a commercial reason to report favorably. An independent laboratory sells the reliability of its results, so its incentive runs the other direction.

Validated Methods Are Reproducible

The laboratories operate under established analytical chemistry standards using calibrated instrumentation. Quantity is measured against a calibration curve printed on the certificate, with its correlation coefficient shown, so the basis of the measurement is visible rather than asserted. The same sample submitted twice should return the same answer.

The Document Travels With the Work

Every certificate is signed by a named analyst or operations manager at the laboratory, with a direct contact address and the dates the sample was received and reported. That is documentation you can file with a protocol, hand to a reviewer, or reference in a methods section. A self-issued sheet carries none of that weight.

Manufacturing runs in U.S. GMP facilities in Akron, Ohio, with chain of custody records held for each lot.

Verifying at Source

Check the Certificate With the Laboratory

You do not have to take a published copy on faith. Every certificate in the library carries a document number and a route back to the laboratory that issued it.

MDx BioAnalytical Laboratory, Inc.

Certificates carry a certificate of analysis identifier and a QC tracking number. Search the identifier at mdxbiolabs.com under the Certificates of Analysis tab. The QR code printed on the document opens the same record.

BioRegen

Certificates carry a COA number and a security key. Enter both at bioregen.com/verify. The QR code printed on the document opens the same record.

Each certificate also names the person who signed it, with a direct email address at the laboratory, if you would rather ask them.

If a document number does not resolve at the laboratory, email help@biolongevitylabs.com and it will be investigated.

Reading the Numbers

How to Read Your Certificate

Most questions about certificates come down to a handful of fields.

Purity percentage

The product page states the minimum specification the lot has to clear. The certificate states what the lot actually measured, which normally sits above it. A specification of 99% with a measured result of 99.6% means the lot cleared the floor with room to spare.

Determined content

This is the quantity of compound the laboratory measured in the vial, reported in milligrams against the labeled quantity. Measured content normally sits at or above the label rather than below it, because vials are filled with an allowance for handling and transfer loss.

Conforms, over-conforming, and pass

Some certificates carry a verdict column alongside each result. Conforms means the result meets the specification. Over-conforming means the result sits above the specification rather than failing it, which is most common on quantity. Pass is used on endotoxin, where the result is measured against a ceiling rather than a target.

Retention time

On the chromatogram, the main peak is the target compound. Its position and area are what the purity figure is calculated from. Small peaks at other positions are related substances counted against that figure.

Molecular weight and compound identifiers

The mass spectrometry section reports the measured mass. Compare it to the theoretical mass for the sequence. Certificates that print the molecular formula, the theoretical molecular weight, the CAS number, and the PubChem CID let you make that comparison without leaving the document. Salt forms such as acetate will read higher than the free base, which is expected rather than a discrepancy.

Test dates

Certificates show when the sample reached the laboratory and when the analysis was reported. Those dates belong to the sample, not to the certificate’s publication date, so they are the figures to cite in a methods section.

Lyophilized material stored at negative 20 degrees Celsius holds for three to five years. Reconstituted material is intended for short-term use under sterile conditions.

FAQ

Common Questions About COAs

COA Process

Verify First, Then Order

Every compound in the catalog has its current lot documented in the library. Check the certificate, confirm the numbers against your protocol requirements, then order.
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