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FOXO4-DRI (10 mg)

FOXO4-DRI is a synthetic peptide designed to selectively induce apoptosis in senescent cells, which are cells that have stopped dividing but remain metabolically active. These cells contribute to aging and various age-related diseases through their pro-inflammatory secretions, known as the senescence-associated secretory phenotype (SASP).

US$274.97

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SKU FOXO-10MG Category Tag Brand:

FOXO4-DRI Peptide Description

FOXO4-DRI (FOXO4-D-Retro-Inverso) is a synthetic peptide designed to disrupt the interaction between the FOXO4 transcription factor and p53, a key regulator of apoptosis. This disruption allows p53 to induce apoptosis in senescent cells, which are cells that have stopped dividing and contribute to aging and various diseases. The peptide has shown promise in selectively targeting and eliminating senescent cells, thereby restoring tissue homeostasis and offering potential therapeutic benefits in several conditions.

FOXO4-D-Retro-Inverso Structure

Molecular Formula: C228H388N86O64

Molecular Weight: 5358 g/mol

Synonyms: 

  • Forkhead box protein 04
  • Proxofim
  • FOXO4a
  • AFX
  • AFX1
  • MLLT7
  • FOXO 4-DRI
  • EX-A7431

Research Areas:

  • Cancer Research
  • Pulmonary Fibrosis
  • Age-Related Conditions
  • Cartilage Regeneration

Source: Uniprot

Weight 0.250 oz
Dimensions 0.625 × 0.625 × 1.5 in
Dutify Classification ID

6064

Scientific Reviewer

Scientifically reviewed by Dr. Ky H. Le, MD. Dr. Le is a board-certified family medicine physician with over 20 years of clinical experience. Dr. Le validates the scientific accuracy of all technical content and research citations.

Disclaimer: For Research Purposes Only

This content is provided strictly for research purposes and does not constitute an endorsement or recommendation for the non-laboratory application or improper handling of peptides designed for research. The information, including discussions about specific peptides and their researched benefits, is presented for informational purposes only and must not be construed as health, clinical, or legal guidance, nor an encouragement for non-research use in humans. Peptides described here are solely for use in structured scientific study by authorized individuals. We advise consulting with research experts, medical practitioners, or legal counsel prior to any decisions about obtaining or utilizing these peptides. The expectation of responsible, ethical utilization of this information for legitimate investigative and scholarly objectives is paramount. This notice is dynamic and governs all provided content on research peptides.

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