The BioLongevity Labs NAD+/MOTS-c/5-Amino-1MQ Blend unites three distinct compounds that converge on cellular energy, mitochondrial function, and metabolic regulation. Together, their mechanisms are designed to:
Enhance mitochondrial and cellular energy balance.
The BioLongevity Labs NAD+/MOTS-c/5-Amino-1MQ Blend unites three distinct compounds that converge on cellular energy, mitochondrial function, and metabolic regulation:
NAD+ (100 mg) replenishes the central redox cofactor required for metabolism, DNA repair, and sirtuin activation [1][2][3].
MOTS-c (10 mg) is a mitochondria-derived peptide that activates AMPK, regulates nuclear gene expression under metabolic stress, and enhances insulin sensitivity [4][5][6].
5-Amino-1MQ (10 mg) inhibits NNMT, raising NAD+ levels while modulating histone methylation and fat metabolism pathways [7][8][9].
Together, their mechanisms are designed to:
Enhance mitochondrial and cellular energy balance by restoring NAD+ pools and activating AMPK [1][4][7].
Improve metabolic health by reducing adiposity, sustaining muscle function, and optimizing glucose regulation [2][5][8].
Support cognitive and longevity research through effects on neuroinflammation, oxidative stress, and cellular senescence [3][6][9].
Peptide Structures
NAD+ (Nicotinamide Adenine Dinucleotide)
Molecular Formula: C₂₁H₂₇N₇O₁₄P₂
Molecular Weight: 663.43 g/mol
PubChem CID: 925
CAS Number: 53-84-9
Synonyms: β-Nicotinamide adenine dinucleotide, DPN, Coenzyme I, Diphosphopyridine nucleotide
MOTS-c (Mitochondrial Open Reading Frame of the 12S rRNA-c)
NAD+ plays a vital role in redox reactions and sirtuin activation. Restoring NAD+ levels in aging and metabolic stress models improved glucose tolerance, mitochondrial function, and overall health [1]. MOTS-c translocates to the nucleus during metabolic stress to regulate antioxidant and glucose metabolism genes via AMPK activation [4]. 5-Amino-1MQ further boosts NAD+ by inhibiting NNMT, enhancing redox balance and mitochondrial efficiency [7].
Metabolic Regulation & Obesity Research
NAD+ depletion contributes to obesity and metabolic disorders; replenishment strategies improve metabolic homeostasis [2]. MOTS-c prevents diet-induced obesity and insulin resistance by improving glucose utilization and maintaining adipose homeostasis [5]. 5-Amino-1MQ reduces white adipose tissue and body weight in preclinical obesity models without affecting appetite, highlighting its direct metabolic actions [8].
Neuroprotection & Longevity
NAD+ enhancement has been shown to reduce neuroinflammation and improve cognition in models of neurodegeneration [3]. MOTS-c enhances memory formation and protects against neuroinflammation, with benefits observed in Alzheimer’s and metabolic dysfunction models [6]. 5-Amino-1MQ alters histone methylation and metabolic programs in cancer and aging models, representing a promising target for longevity and oncology research [9].
Note: This product is supplied strictly for investigational research use only.
Certificate of Analysis (COA) for Every Batch
A Certificate of Analysis (COA) is a document that verifies a compound’s identity, purity, and batch quality through independent laboratory testing. Every compound from BioLongevity Labs ships with a COA tied to its specific batch, so researchers can confirm exactly what they received before it enters a protocol.
Each COA reports results from third-party laboratory analysis, including:
High-performance liquid chromatography (HPLC) for purity, typically confirmed at 99% or higher
Liquid chromatography mass spectrometry (LC-MS) for molecular identity and mass confirmation
Sterility and endotoxin screening where applicable
Chemical contaminant and residual solvent checks
COAs are sourced from independent certified labs rather than in-house testing alone, giving researchers a verifiable record of molecular integrity for each batch. All compounds are supplied for research use only.
Scientifically reviewed by Dr. Ky H. Le, MD. Dr. Le is a board-certified family medicine physician with over 20 years of clinical experience. Dr. Le validates the scientific accuracy of all technical content and research citations.
Disclaimer: For Research Purposes Only
This content is provided strictly for research purposes and does not constitute an endorsement or recommendation for the non-laboratory application or improper handling of peptides designed for research. The information, including discussions about specific peptides and their researched benefits, is presented for informational purposes only and must not be construed as health, clinical, or legal guidance, nor an encouragement for non-research use. Peptides described here are solely for use in structured scientific study by authorized individuals. We advise consulting with research experts, medical practitioners, or legal counsel prior to any decisions about obtaining or utilizing these peptides. The expectation of responsible, ethical utilization of this information for legitimate investigative and scholarly objectives is paramount. This notice is dynamic and governs all provided content on research peptides.
